Sunday, September 13, 2009

Swine flu shots may start early October


Health and Human Services Secretary Kathleen Sebelius said that the first round of swine flu vaccine could be ready by early October




The nation's first round of swine flu shots could begin sooner than expected, with some vaccine available as early as the first week of October, Health and Human Services Secretary Kathleen Sebelius said Sunday.

Sebelius said she is confident the vaccine will be available early enough to beat the peak of the expected flu season this fall and that early doses are intended for health care workers and other high-priority groups.

"We're on track to have an ample supply rolling by the middle of October. But we may have some early vaccine as early as the first full week in October. We'll get the vaccine out the door as fast as it rolls off the production line," she told ABC's "This Week."

The possibility of early shots follows encouraging news from last week about the swine flu vaccine. Researchers have discovered that one dose instead of two could be enough for healthy adults, and protection could begin once vaccinated within 10 days instead of three weeks.

"That's great, which means we'll have a lot more vaccine," she said. "We also have seen a robust immune response within 10 days, instead of three weeks as was feared."

Sebelius said the vaccine doses will be distributed immediately to designated locations across the country once they are available.

"Every state has a plan saying these are the sites to get the vaccine as quickly as possible into people's arms. That's where the distribution will go," she said.

"So, the first week in October, we expect some of the vaccine to begin to roll, and by mid-October, to have the kind of supplies we were talking about. But we may have some available earlier. And we'll get it out to states as fast as it comes off the production lines," Sebelius said.

One dose means tight supplies of H1N1 vaccine won't be stretched so badly. Had it taken twice that dose, or two shots apiece, half as many people could have received the vaccine.

The winter flu vaccine is widely available now, and health authorities urged people last week to get shots now before swine flu shots start arriving.

In addition to concerns about swine flu, doctors also expect some garden-variety flu this fall as well, an illness that typically kills 36,000 Americans and hospitalizes 200,000 each year.

The officials expect about 50 million doses of swine flu vaccine to reach government warehouses by Oct. 15, and 20 million more to be ready each week after that until 195 million is reached.

Then those lots must be shipped to health centers, schools and other vaccination sites, people must be injected, and each must develop immunity. Immune responses are different in each individual, but the clinical trials suggest that most will be protected after 8 to 10 days.

So if the epidemic’s peak comes in late October, millions of people are likely to catch the flu before the vaccine is available.

“A month would have made a huge difference,” said Ira M. Longini Jr., an author of a report by an epidemic-modeling team at the Fred Hutchinson Cancer Research Center in Seattle and the University of Washington.

If one shot turns out to be protective in children and if the flu peaks in late December, as the 1968 Hong Kong flu did, “we could be O.K.,” Dr. Longini said. “But that’s a lot of ifs.”

In response, federal officials said there was no way to tell whether the pessimistic models would be right, since flu peaks at different times in different regions each year.

Health and Human Services Secretary Kathleen Sebelius"We're on track to have an ample supply rolling by the middle of October. But we may have some early vaccine as early as the first full week in October. We'll get the vaccine out the door as fast as it rolls off the production line," she told ABC's "This Week."The city has offered every school kid a free swine flu vaccine when it becomes available.

The winter flu vaccine is widely available now, and health authorities urged people last week to get shots now before swine flu vaccines start arriving.

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Health Secretary Kathleen Sebelius on Sunday said the United States now expects to receive the first batch of swine flu vaccine in early October, a few weeks earlier than expected."The first week in October, we expect some of the vaccine to begin to roll," Sebelius said.On Friday, the health secretary said clinical trails had shown a single dose of the vaccine was enough to ensure immunity within 10 days.

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A White House panel is warning that the H1N1 flu virus could infect up to half of the American population in the coming months ad may lead to as many as 90,000 deaths

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